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Revisiting Connectivity Map from a gene co-expression network analysis
The Connectivity Map (CMap) is a tool that has been extensively utilized to study drug repositioning and side-effect prediction. However, most of these analyses rely on signature genes, ignoring the pathways by which those genes are regulated, as well as the functional overlap of redundant genes. Th...
Autores principales: | Liu, Wei, Tu, Wei, Li, Li, Liu, Yingfu, Wang, Shaobo, Li, Ling, Tao, Huan, He, Huaqin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090433/ https://www.ncbi.nlm.nih.gov/pubmed/30112021 http://dx.doi.org/10.3892/etm.2018.6275 |
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