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Normalizing JMJD6 Expression in Rat Spinal Dorsal Horn Alleviates Hyperalgesia Following Chronic Constriction Injury

Jumonji domain-containing protein 6 (JMJD6) is a homolog of hypoxia-inducible factor (HIF) asparaginyl hydroxylase, an inhibitor of HIF. HIF-1α is known to participate in neuropathic pain (NPP) during chronic constriction injury (CCI); however, the roles of JMJD6 in NPP have not been systematically...

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Detalles Bibliográficos
Autores principales: Mo, Cheng, Xu, Mengyuan, Wen, Cen, Chang, Ruimin, Huang, Changsheng, Zou, Wangyuan, Zhu, Xiaoyan, Guo, Qulian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090481/
https://www.ncbi.nlm.nih.gov/pubmed/30131674
http://dx.doi.org/10.3389/fnins.2018.00542