The Intracellular Cleavage Product of the NG2 Proteoglycan Modulates Translation and Cell-Cycle Kinetics via Effects on mTORC1/FMRP Signaling

The NG2 proteoglycan is expressed by oligodendrocyte precursor cells (OPCs) and is abundantly expressed by tumors such as melanoma and glioblastoma. Functions of NG2 include an influence on proliferation, migration and neuromodulation. Similar to other type-1 membrane proteins, NG2 undergoes proteol...

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Detalles Bibliográficos
Autores principales: Nayak, Tanmoyita, Trotter, Jacqueline, Sakry, Dominik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090502/
https://www.ncbi.nlm.nih.gov/pubmed/30131676
http://dx.doi.org/10.3389/fncel.2018.00231

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090502/
https://www.ncbi.nlm.nih.gov/pubmed/30131676
http://dx.doi.org/10.3389/fncel.2018.00231

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