Epigenetic regulation of brain region-specific microglia clearance activity

The rapid elimination of dying neurons and non-functional synapses in the brain is carried out by microglia, the resident myeloid cells of the brain. Here we show that microglia clearance activity in the adult brain is regionally regulated and depends on the rate of neuronal attrition. Cerebellar, b...

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Detalles Bibliográficos
Autores principales: Ayata, Pinar, Badimon, Ana, Strasburger, Hayley J., Duff, Mary Kaye, Montgomery, Sarah E., Loh, Yong-Hwee E., Ebert, Anja, Pimenova, Anna A., Ramirez, Brianna R., Chan, Andrew T., Sullivan, Josefa M., Purushothaman, Immanuel, Scarpa, Joseph R., Goate, Alison M., Busslinger, Meinrad, Shen, Li, Losic, Bojan, Schaefer, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090564/
https://www.ncbi.nlm.nih.gov/pubmed/30038282
http://dx.doi.org/10.1038/s41593-018-0192-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090564/
https://www.ncbi.nlm.nih.gov/pubmed/30038282
http://dx.doi.org/10.1038/s41593-018-0192-3

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