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A suppressive role of guanine nucleotide-binding protein subunit beta-4 inhibited by DNA methylation in the growth of anti-estrogen resistant breast cancer cells

BACKGROUND: Breast cancer is the most common malignancy in women worldwide. Although the endocrine therapy that targets estrogen receptor α (ERα) signaling has been well established as an effective adjuvant treatment for patients with ERα-positive breast cancers, long-term exposure may eventually le...

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Detalles Bibliográficos
Autores principales: Wang, Bo, Li, Dongping, Rodriguez-Juarez, Rocio, Farfus, Allison, Storozynsky, Quinn, Malach, Megan, Carpenter, Emily, Filkowski, Jody, Lykkesfeldt, Anne E., Kovalchuk, Olga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090602/
https://www.ncbi.nlm.nih.gov/pubmed/30103729
http://dx.doi.org/10.1186/s12885-018-4711-0