Accurate Titration of Infectious AAV Particles Requires Measurement of Biologically Active Vector Genomes and Suitable Controls

Although the clinical use of recombinant adeno-associated virus (rAAV) vectors is constantly increasing, the development of suitable quality control methods is still needed for accurate vector characterization. Among the quality criteria, the titration of infectious particles is critical to determin...

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Detalles Bibliográficos
Autores principales: François, Achille, Bouzelha, Mohammed, Lecomte, Emilie, Broucque, Frédéric, Penaud-Budloo, Magalie, Adjali, Oumeya, Moullier, Philippe, Blouin, Véronique, Ayuso, Eduard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090651/
https://www.ncbi.nlm.nih.gov/pubmed/30112419
http://dx.doi.org/10.1016/j.omtm.2018.07.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090651/
https://www.ncbi.nlm.nih.gov/pubmed/30112419
http://dx.doi.org/10.1016/j.omtm.2018.07.004

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