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The plasticity of primary microglia and their multifaceted effects on endogenous neural stem cells in vitro and in vivo

BACKGROUND: Microglia—the resident immune cells of the brain—are activated after brain lesions, e.g., cerebral ischemia, and polarize towards a classic “M1” pro-inflammatory or an alternative “M2” anti-inflammatory phenotype following characteristic temporo-spatial patterns, contributing either to s...

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Detalles Bibliográficos
Autores principales: Vay, Sabine Ulrike, Flitsch, Lea Jessica, Rabenstein, Monika, Rogall, Rebecca, Blaschke, Stefan, Kleinhaus, Judith, Reinert, Noémie, Bach, Annika, Fink, Gereon Rudolf, Schroeter, Michael, Rueger, Maria Adele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090672/
https://www.ncbi.nlm.nih.gov/pubmed/30103769
http://dx.doi.org/10.1186/s12974-018-1261-y