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The plasticity of primary microglia and their multifaceted effects on endogenous neural stem cells in vitro and in vivo
BACKGROUND: Microglia—the resident immune cells of the brain—are activated after brain lesions, e.g., cerebral ischemia, and polarize towards a classic “M1” pro-inflammatory or an alternative “M2” anti-inflammatory phenotype following characteristic temporo-spatial patterns, contributing either to s...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090672/ https://www.ncbi.nlm.nih.gov/pubmed/30103769 http://dx.doi.org/10.1186/s12974-018-1261-y |