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Asthmatic bronchial epithelial cells promote the establishment of a Hyaluronan-enriched, leukocyte-adhesive extracellular matrix by lung fibroblasts

BACKGROUND: Airway inflammation is a hallmark of asthma. Alterations in extracellular matrix (ECM) hyaluronan (HA) content have been shown to modulate the recruitment and retention of inflammatory cells. Bronchial epithelial cells (BECs) regulate the activity of human lung fibroblasts (HLFs); howeve...

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Detalles Bibliográficos
Autores principales: Reeves, Stephen R., Kang, Inkyung, Chan, Christina K., Barrow, Kaitlyn A., Kolstad, Tessa K., White, Maria P., Ziegler, Steven F., Wight, Thomas N., Debley, Jason S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090698/
https://www.ncbi.nlm.nih.gov/pubmed/30071849
http://dx.doi.org/10.1186/s12931-018-0849-1