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Carnosine selectively inhibits migration of IDH-wildtype glioblastoma cells in a co-culture model with fibroblasts

BACKGROUND: Glioblastoma (GBM) is a tumor of the central nervous system. After surgical removal and standard therapy, recurrence of tumors is observed within 6–9 months because of the high migratory behavior and the infiltrative growth of cells. Here, we investigated whether carnosine (β-alanine-l-h...

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Detalles Bibliográficos
Autores principales: Oppermann, Henry, Dietterle, Johannes, Purcz, Katharina, Morawski, Markus, Eisenlöffel, Christian, Müller, Wolf, Meixensberger, Jürgen, Gaunitz, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090706/
https://www.ncbi.nlm.nih.gov/pubmed/30123089
http://dx.doi.org/10.1186/s12935-018-0611-2