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Carnosine selectively inhibits migration of IDH-wildtype glioblastoma cells in a co-culture model with fibroblasts
BACKGROUND: Glioblastoma (GBM) is a tumor of the central nervous system. After surgical removal and standard therapy, recurrence of tumors is observed within 6–9 months because of the high migratory behavior and the infiltrative growth of cells. Here, we investigated whether carnosine (β-alanine-l-h...
Autores principales: | Oppermann, Henry, Dietterle, Johannes, Purcz, Katharina, Morawski, Markus, Eisenlöffel, Christian, Müller, Wolf, Meixensberger, Jürgen, Gaunitz, Frank |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090706/ https://www.ncbi.nlm.nih.gov/pubmed/30123089 http://dx.doi.org/10.1186/s12935-018-0611-2 |
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