Cargando…

The effect of intracerebroventricular administration of orexin receptor type 2 antagonist on pentylenetetrazol-induced kindled seizures and anxiety in rats

BACKGROUND: Current antiepileptic drugs are not able to prevent recurrent seizures in all patients. Orexins are excitatory hypothalamic neuropeptides that their receptors (Orx1R and Orx2R) are found almost in all major regions of the brain. Pentylenetetrazol (PTZ)-induced kindling is a known experim...

Descripción completa

Detalles Bibliográficos
Autores principales:	Asadi, Saeedeh, Roohbakhsh, Ali, Shamsizadeh, Ali, Fereidoni, Masoud, Kordijaz, Elham, Moghimi, Ali
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090721/ https://www.ncbi.nlm.nih.gov/pubmed/30103703 http://dx.doi.org/10.1186/s12868-018-0445-9

Ejemplares similares

The effect of Zataria multiflora Boiss hydroalcoholic extract and fractions in pentylenetetrazole-induced kindling in mice
por: Shamsizadeh, Ali, et al.
Publicado: (2016)

Montelukast reduces seizures in pentylenetetrazol-kindled mice
por: Fleck, J., et al.
Publicado: (2016)

The Protective Effect of Auraptene Against Oxidative Stress and Pentylenetetrazol-Induced Chemical Kindling in Mice
por: Etemad, Leila, et al.
Publicado: (2019)

Preparation and Evaluation of Carbamazepine Solid Lipid Nanoparticle for Alleviating Seizure Activity in Pentylenetetrazole-Kindled Mice
por: Qushawy, Mona, et al.
Publicado: (2019)

Ferroptosis Induction in Pentylenetetrazole Kindling and Pilocarpine-Induced Epileptic Seizures in Mice
por: Mao, Xiao-Yuan, et al.
Publicado: (2019)

Effect of lamotrigine on seizure development in a rat pentylenetetrazole kindling model
por: Chen, Yishu, et al.
Publicado: (2017)

Effects of Satureja Bachtiarica Essential Oil in Preventing Seizure in Pentylenetetrazol-Kindled Mice
por: Rabiei, Zahra, et al.
Publicado: (2022)

Overexpression of zinc-α2-glycoprotein suppressed seizures and seizure-related neuroflammation in pentylenetetrazol-kindled rats
por: Liu, Ying, et al.
Publicado: (2018)

Therapeutic Effects of Oleuropein in Improving Seizure, Oxidative Stress and Cognitive Disorder in Pentylenetetrazole Kindling Model of Epilepsy in Mice
por: Asgharzade, Samira, et al.
Publicado: (2020)

Anti-kindling Effect of Bezafibrate, a Peroxisome Proliferator-activated Receptors Alpha Agonist, in Pentylenetetrazole Induced Kindling Seizure Model
por: Saha, Lekha, et al.
Publicado: (2014)

The effect of pretreatment with hydroalcoholic extract of Alpinia officinarum rhizome on seizure severity and memory impairment in pentylenetetrazol-induced kindling model of seizure in rat
por: Solati, Kamal, et al.
Publicado: (2019)

Carveol Attenuates Seizure Severity and Neuroinflammation in Pentylenetetrazole-Kindled Epileptic Rats by Regulating the Nrf2 Signaling Pathway
por: Alvi, Arooj Mohsin, et al.
Publicado: (2021)

l-Carnitine Modulates Epileptic Seizures in Pentylenetetrazole-Kindled Rats via Suppression of Apoptosis and Autophagy and Upregulation of Hsp70
por: Hussein, Abdelaziz M., et al.
Publicado: (2018)

Embelin Prevents Seizure and Associated Cognitive Impairments in a Pentylenetetrazole-Induced Kindling Zebrafish Model
por: Kundap, Uday Praful, et al.
Publicado: (2019)

Anticonvulsant Effects of Dingxian Pill in Pentylenetetrazol-Kindled Rats
por: Zhu, Yudan, et al.
Publicado: (2019)

Effects of GLP-1 Receptor Activation on a Pentylenetetrazole—Kindling Rat Model
por: Hussein, Abdelaziz M., et al.
Publicado: (2019)

Administration of orexin receptor 1 antagonist into the rostral ventromedial medulla increased swim stress-induced antinociception in rat
por: Soliemani, Neda, et al.
Publicado: (2016)

Effects of Lycopene and Sodium Valproate on Pentylenetetrazol-Induced Kindling in Mice
por: Kumar, Vinay, et al.
Publicado: (2016)

Endocannabinoid System and TRPV1 Receptors in the Dorsal Hippocampus of the Rats Modulate Anxiety-like Behaviors
por: Hakimizadeh, Elham, et al.
Publicado: (2012)

Protective Effects of Intranasally Administrated Oxytocin-Loaded Nanoparticles on Pentylenetetrazole-Kindling Epilepsy in Terms of Seizure Severity, Memory, Neurogenesis, and Neuronal Damage
por: Sahin, Hakan, et al.
Publicado: (2022)

Lamotrigine Decreased Hippocampal Damage and Improved Vascular Risk Markers in a Rat Model of Pentylenetetrazole Induced Kindling Seizure
por: Haggag, Basma S, et al.
Publicado: (2014)

Beta Lactams Antibiotic Ceftriaxone Modulates Seizures, Oxidative Stress and Connexin 43 Expression in Hippocampus of Pentylenetetrazole Kindled Rats
por: Hussein, Abdelaziz M., et al.
Publicado: (2016)

Resveratrol is Neuroprotective and Improves Cognition in Pentylenetetrazole-kindling Model of Epilepsy in Rats
por: Meng, X. J., et al.
Publicado: (2014)

Antiepileptic and Antioxidant Effect of Brassica nigra on Pentylenetetrazol-Induced Kindling in Mice
por: Kiasalari, Zahra, et al.
Publicado: (2012)

Anticonvulsant and Neuroprotective Activities of Phragmanthera austroarabica Extract in Pentylenetetrazole-Kindled Mice
por: Aldawsari, Hibah M., et al.
Publicado: (2017)

Anticonvulsant and Antioxidant Effects of Pitavastatin Against Pentylenetetrazol-Induced Kindling in Mice
por: Faghihi, Nastaran, et al.
Publicado: (2017)

Investigating Cardiac Morphological Alterations in a Pentylenetetrazol-Kindling Model of Epilepsy
por: Akyuz, Enes, et al.
Publicado: (2020)

Anticonvulsant and ameliorative effects of pioglitazone on cognitive deficits, inflammation and apoptosis in the hippocampus of rat pups exposed to febrile seizure
por: Hussein, Hussein Allawi, et al.
Publicado: (2019)

Myristica Fragrans Houtt Extract Attenuates Neuronal Loss and Glial Activation in Pentylenetetrazol-Induced Kindling Model
por: Ghorbanian, Davoud, et al.
Publicado: (2019)

Behavioral and Neurochemical Consequences of Pentylenetetrazol-Induced Kindling in Young and Middle-Aged Rats
por: Hoeller, Alexandre Ademar, et al.
Publicado: (2017)

Alteration of Extracellular Matrix Molecules and Perineuronal Nets in the Hippocampus of Pentylenetetrazol-Kindled Mice
por: Ueno, Hiroshi, et al.
Publicado: (2019)

Behavioral and Brain Structural Changes in Kindled Rats Induced by Coriaria Lactone/Pentylenetetrazol
por: He, Shixu, et al.
Publicado: (2021)

Parameters of Oxidative Stress and Behavior in Animals Treated with Dexametasone and Submitted to Pentylenetetrazol Kindling
por: Guzzo, Edson Fernando Muller, et al.
Publicado: (2021)

Effects of atorvastatin and metformin on development of pentylenetetrazole-induced seizure in mice
por: Zeyghami, Mohammad Ali, et al.
Publicado: (2020)

Potentiation of pentylenetetrazole-induced neuronal damage by dimethyl sulfoxide in chemical kindling model in rats
por: Kumari, Puja, et al.
Publicado: (2018)

Anti-Oxidant and Anti-Apoptotic Effects of Berberine in Pentylenetetrazole-Induced Kindling Model in Rat
por: Guna, Vaishali, et al.
Publicado: (2018)

Combination of levetiracetam with sodium selenite prevents pentylenetetrazole-induced kindling and behavioral comorbidities in rats
por: Rehman, Zohabia, et al.
Publicado: (2022)

Enhanced Astrocyte Activity and Excitatory Synaptic Function in the Hippocampus of Pentylenetetrazole Kindling Model of Epilepsy
por: Díaz, Franco, et al.
Publicado: (2023)

Pentylenetetrazole-Induced Seizures Are Increased after Kindling, Exhibiting Vitamin-Responsive Correlations to the Post-Seizures Behavior, Amino Acids Metabolism and Key Metabolic Regulators in the Rat Brain
por: Aleshin, Vasily A., et al.
Publicado: (2023)

Semaglutide attenuates seizure severity and ameliorates cognitive dysfunction by blocking the NLR family pyrin domain containing 3 inflammasome in pentylenetetrazole-kindled mice
por: Wang, Lei, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_s3j183hiu7lpafp1ui6eojifnn