Membrane binding, internalization, and sorting of alpha-synuclein in the cell

Alpha-synuclein (aSyn) plays a crucial role in Parkinson’s disease (PD) and other synucleinopathies, since it misfolds and accumulates in typical proteinaceous inclusions. While the function of aSyn is thought to be related to vesicle binding and trafficking, the precise molecular mechanisms linking...

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Detalles Bibliográficos
Autores principales: Masaracchia, Caterina, Hnida, Marilena, Gerhardt, Ellen, Lopes da Fonseca, Tomás, Villar-Pique, Anna, Branco, Tiago, Stahlberg, Markus A., Dean, Camin, Fernández, Claudio O., Milosevic, Ira, Outeiro, Tiago F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090819/
https://www.ncbi.nlm.nih.gov/pubmed/30107856
http://dx.doi.org/10.1186/s40478-018-0578-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090819/
https://www.ncbi.nlm.nih.gov/pubmed/30107856
http://dx.doi.org/10.1186/s40478-018-0578-1

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