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Early increase in blood supply (EIBS) is associated with tumor risk in the Azoxymethane model of colon cancer

BACKGROUND: The present study aimed to investigate the role of blood supply in early tumorigenesis in colorectal cancer. We leveraged the renin angiotensin system (RAS) to alter colonic blood supply and determine the effect on tumor initiation and progression. METHODS: To test the effect of blood su...

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Detalles Bibliográficos
Autores principales: Ruderman, Sarah, Eshein, Adam, Valuckaite, Vesta, Dougherty, Urszula, Almoghrabi, Anas, Gomes, Andrew, Singh, Ajaypal, Pabla, Baldeep, Roy, Hemant K., Hart, John, Bissonnette, Marc, Konda, Vani, Backman, Vadim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090821/
https://www.ncbi.nlm.nih.gov/pubmed/30103733
http://dx.doi.org/10.1186/s12885-018-4709-7