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Early increase in blood supply (EIBS) is associated with tumor risk in the Azoxymethane model of colon cancer
BACKGROUND: The present study aimed to investigate the role of blood supply in early tumorigenesis in colorectal cancer. We leveraged the renin angiotensin system (RAS) to alter colonic blood supply and determine the effect on tumor initiation and progression. METHODS: To test the effect of blood su...
Autores principales: | Ruderman, Sarah, Eshein, Adam, Valuckaite, Vesta, Dougherty, Urszula, Almoghrabi, Anas, Gomes, Andrew, Singh, Ajaypal, Pabla, Baldeep, Roy, Hemant K., Hart, John, Bissonnette, Marc, Konda, Vani, Backman, Vadim |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090821/ https://www.ncbi.nlm.nih.gov/pubmed/30103733 http://dx.doi.org/10.1186/s12885-018-4709-7 |
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