Nanopore sequencing and full genome de novo assembly of human cytomegalovirus TB40/E reveals clonal diversity and structural variations

BACKGROUND: Human cytomegalovirus (HCMV) has a double-stranded DNA genome of approximately 235 Kbp that is structurally complex including extended GC-rich repeated regions. Genomic recombination events are frequent in HCMV cultures but have also been observed in vivo. Thus, the assembly of HCMV whol...

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Detalles Bibliográficos
Autores principales: Karamitros, Timokratis, van Wilgenburg, Bonnie, Wills, Mark, Klenerman, Paul, Magiorkinis, Gkikas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090854/
https://www.ncbi.nlm.nih.gov/pubmed/30068288
http://dx.doi.org/10.1186/s12864-018-4949-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090854/
https://www.ncbi.nlm.nih.gov/pubmed/30068288
http://dx.doi.org/10.1186/s12864-018-4949-6

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