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Gene expression analysis indicates reduced memory and cognitive functions in the hippocampus and increase in synaptic reorganization in the frontal cortex 3 weeks after MDMA administration in Dark Agouti rats

BACKGROUND: 3,4-methylenedioxymethamphetamine (MDMA, “ecstasy”) is a widely used entactogenic drug known to impair cognitive functions on the long-run. Both hippocampal and frontal cortical regions have well established roles in behavior, memory formation and other cognitive tasks and damage of thes...

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Detalles Bibliográficos
Autores principales: Petschner, Peter, Tamasi, Viola, Adori, Csaba, Kirilly, Eszter, Ando, Romeo D., Tothfalusi, Laszlo, Bagdy, Gyorgy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090855/
https://www.ncbi.nlm.nih.gov/pubmed/30071829
http://dx.doi.org/10.1186/s12864-018-4929-x