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A new hypothesis for Parkinson’s disease pathogenesis: GTPase-p38 MAPK signaling and autophagy as convergence points of etiology and genomics

The combination of genetics and genomics in Parkinson´s disease has recently begun to unveil molecular mechanisms possibly underlying disease onset and progression. In particular, catabolic processes such as autophagy have been increasingly gaining relevance as post-mortem evidence and experimental...

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Detalles Bibliográficos
Autores principales: Obergasteiger, Julia, Frapporti, Giulia, Pramstaller, Peter P., Hicks, Andrew A., Volta, Mattia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090926/
https://www.ncbi.nlm.nih.gov/pubmed/30071902
http://dx.doi.org/10.1186/s13024-018-0273-5