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MASTL induces Colon Cancer progression and Chemoresistance by promoting Wnt/β-catenin signaling

BACKGROUND: Chemotherapeutic agents that modulate cell cycle checkpoints and/or tumor-specific pathways have shown immense promise in preclinical and clinical studies aimed at anti-cancer therapy. MASTL (Greatwall in Xenopus and Drosophila), a serine/threonine kinase controls the final G2/M checkpoi...

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Detalles Bibliográficos
Autores principales: Uppada, Srijayaprakash Babu, Gowrikumar, Saiprasad, Ahmad, Rizwan, Kumar, Balawant, Szeglin, Bryan, Chen, Xi, Smith, J. Joshua, Batra, Surinder K., Singh, Amar B., Dhawan, Punita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090950/
https://www.ncbi.nlm.nih.gov/pubmed/30068336
http://dx.doi.org/10.1186/s12943-018-0848-3