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Tricho-rhino-phalangeal syndrome 1 protein functions as a scaffold required for ubiquitin-specific protease 4-directed histone deacetylase 2 de-ubiquitination and tumor growth

BACKGROUND: Although numerous studies have reported that tricho-rhino-phalangeal syndrome type I (TRPS1) protein, the only reported atypical GATA transcription factor, is overexpressed in various carcinomas, the underlying mechanism(s) by which it contributes to cancer remain unknown. METHODS: Both...

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Detalles Bibliográficos
Autores principales: Wang, Yuzhi, Zhang, Jun, Wu, Lele, Liu, Weiguang, Wei, Guanyun, Gong, Xue, Liu, Yan, Ma, Zhifang, Ma, Fei, Thiery, Jean Paul, Chen, Liming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090974/
https://www.ncbi.nlm.nih.gov/pubmed/30071870
http://dx.doi.org/10.1186/s13058-018-1018-7