Regulation of diabetic cardiomyopathy by caloric restriction is mediated by intracellular signaling pathways involving ‘SIRT1 and PGC-1α’

BACKGROUND: Metabolic disorders such as obesity, insulin resistance and type 2 diabetes mellitus (DM2) are all linked to diabetic cardiomyopathy that lead to heart failure. Cardiomyopathy is initially characterized by cardiomyocyte hypertrophy, followed by mitochondrial dysfunction and fibrosis, bot...

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Detalles Bibliográficos
Autores principales: Waldman, Maayan, Cohen, Keren, Yadin, Dor, Nudelman, Vadim, Gorfil, Dan, Laniado-Schwartzman, Michal, Kornwoski, Ran, Aravot, Dan, Abraham, Nader G., Arad, Michael, Hochhauser, Edith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090985/
https://www.ncbi.nlm.nih.gov/pubmed/30071860
http://dx.doi.org/10.1186/s12933-018-0754-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090985/
https://www.ncbi.nlm.nih.gov/pubmed/30071860
http://dx.doi.org/10.1186/s12933-018-0754-4

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