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STAT3 exacerbates survival of cancer stem-like tumorspheres in EGFR-positive colorectal cancers: RNAseq analysis and therapeutic screening

BACKGROUND: Cancer stem cells are capable of undergoing cell division after surviving cancer therapies, leading to tumor progression and recurrence. Inhibitory agents against cancer stem cells may be therapeutically used for efficiently eradicating tumors. Therefore, the aim of this study was to ide...

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Detalles Bibliográficos
Autores principales: Cheng, Chun-Chia, Liao, Po-Nien, Ho, Ai-Sheng, Lim, Ken-Hong, Chang, Jungshan, Su, Ying-Wen, Chen, Caleb Gon-Shen, Chiang, Ya-Wen, Yang, Bi-Ling, Lin, Huan-Chau, Chang, Yu-Cheng, Chang, Chun-Chao, Chang, Yi-Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090986/
https://www.ncbi.nlm.nih.gov/pubmed/30068339
http://dx.doi.org/10.1186/s12929-018-0456-y