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Erythrocyte P2X(1) receptor expression is correlated with change in haematocrit in patients admitted to the ICU with blood pathogen-positive sepsis

BACKGROUND: Pore-forming proteins released from bacteria or formed as result of complement activation are known to produce severe cell damage. Inhibition of purinergic P2X receptors markedly reduces damage inflicted by cytolytic bacterial toxin and after complement activation in both erythrocytes an...

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Detalles Bibliográficos
Autores principales: Fagerberg, Steen K., Patel, Parth, Andersen, Lars W., Lui, Xiaowen, Donnino, Michael W., Praetorius, Helle A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6091015/
https://www.ncbi.nlm.nih.gov/pubmed/30071869
http://dx.doi.org/10.1186/s13054-018-2100-3