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Erythrocyte P2X(1) receptor expression is correlated with change in haematocrit in patients admitted to the ICU with blood pathogen-positive sepsis
BACKGROUND: Pore-forming proteins released from bacteria or formed as result of complement activation are known to produce severe cell damage. Inhibition of purinergic P2X receptors markedly reduces damage inflicted by cytolytic bacterial toxin and after complement activation in both erythrocytes an...
Autores principales: | Fagerberg, Steen K., Patel, Parth, Andersen, Lars W., Lui, Xiaowen, Donnino, Michael W., Praetorius, Helle A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6091015/ https://www.ncbi.nlm.nih.gov/pubmed/30071869 http://dx.doi.org/10.1186/s13054-018-2100-3 |
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