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Dealing with the adaptive immune system during de novo evolution of genes from intergenic sequences

BACKGROUND: The adaptive immune system of vertebrates has an extraordinary potential to sense and neutralize foreign antigens entering the body. De novo evolution of genes implies that the genome itself expresses novel antigens from intergenic sequences which could cause a problem with this immune s...

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Detalles Bibliográficos
Autores principales: Bekpen, Cemalettin, Xie, Chen, Tautz, Diethard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6091031/
https://www.ncbi.nlm.nih.gov/pubmed/30075701
http://dx.doi.org/10.1186/s12862-018-1232-z