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Dealing with the adaptive immune system during de novo evolution of genes from intergenic sequences
BACKGROUND: The adaptive immune system of vertebrates has an extraordinary potential to sense and neutralize foreign antigens entering the body. De novo evolution of genes implies that the genome itself expresses novel antigens from intergenic sequences which could cause a problem with this immune s...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6091031/ https://www.ncbi.nlm.nih.gov/pubmed/30075701 http://dx.doi.org/10.1186/s12862-018-1232-z |