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Enrichment of cancer stem cells via β-catenin contributing to the tumorigenesis of hepatocellular carcinoma

BACKGROUND: Hepatocellular carcinoma (HCC) is among the deadliest cancers due to its heterogeneity, contributing to chemoresistance and recurrence. Cancer stem-like cells (CSCs) are suggested to play an important role in HCC tumorigenesis. This study investigates the role of Wnt/β-catenin pathway in...

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Detalles Bibliográficos
Autores principales: Pandit, Harshul, Li, Yan, Li, Xuanyi, Zhang, Weizhong, Li, Suping, Martin, Robert C. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6091111/
https://www.ncbi.nlm.nih.gov/pubmed/30075764
http://dx.doi.org/10.1186/s12885-018-4683-0