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Ouabain Does Not Induce Selective Spiral Ganglion Cell Degeneration in Guinea Pigs

Round window membrane (RWM) application of ouabain is known to selectively destroy type I spiral ganglion cells (SGCs) in cochleas of several rodent species, while leaving hair cells intact. This protocol has been used in rats and Mongolian gerbils, but observations in the guinea pig are conflicting...

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Detalles Bibliográficos
Autores principales: Schomann, Timo, Ramekers, Dyan, de Groot, John C. M. J., van der Ploeg, Carola H., Hendriksen, Ferry G. J., Böhringer, Stefan, Klis, Sjaak F. L., Frijns, Johan H. M., Huisman, Margriet A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6091334/
https://www.ncbi.nlm.nih.gov/pubmed/30151372
http://dx.doi.org/10.1155/2018/1568414