Apatinib-loaded lipid nanobubbles combined with ultrasound-targeted nanobubble destruction for synergistic treatment of HepG2 cells in vitro

PURPOSE: Apatinib, an oral small-molecule antiangiogenetic medicine, is used to treat patients with advanced hepatocellular carcinoma. However, its systemic toxic side effects cannot be ignored. The ultrasound (US)-targeted nanobubble destruction technology can minimize systemic drug exposure and ma...

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Detalles Bibliográficos
Autores principales: Tian, Yuhang, Liu, Zhao, Zhang, Lei, Zhang, Jia, Han, Xue, Wang, Qiucheng, Cheng, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6091478/
https://www.ncbi.nlm.nih.gov/pubmed/30127626
http://dx.doi.org/10.2147/OTT.S170786

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6091478/
https://www.ncbi.nlm.nih.gov/pubmed/30127626
http://dx.doi.org/10.2147/OTT.S170786

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