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Spindle Dynamics Model Explains Chromosome Loss Rates in Yeast Polyploid Cells
Faithful chromosome segregation, driven by the mitotic spindle, is essential for organismal survival. Neopolyploid cells from diverse species exhibit a significant increase in mitotic errors relative to their diploid progenitors, resulting in chromosome nondisjunction. In the model system Saccharomy...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6091489/ https://www.ncbi.nlm.nih.gov/pubmed/30131823 http://dx.doi.org/10.3389/fgene.2018.00296 |