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Spindle Dynamics Model Explains Chromosome Loss Rates in Yeast Polyploid Cells

Faithful chromosome segregation, driven by the mitotic spindle, is essential for organismal survival. Neopolyploid cells from diverse species exhibit a significant increase in mitotic errors relative to their diploid progenitors, resulting in chromosome nondisjunction. In the model system Saccharomy...

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Detalles Bibliográficos
Autores principales:	Jelenić, Ivan, Selmecki, Anna, Laan, Liedewij, Pavin, Nenad
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6091489/ https://www.ncbi.nlm.nih.gov/pubmed/30131823 http://dx.doi.org/10.3389/fgene.2018.00296

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