The Guanylate Cyclase C—cGMP Signaling Axis Opposes Intestinal Epithelial Injury and Neoplasia

Guanylate cyclase C (GUCY2C) is a transmembrane receptor expressed on the luminal aspect of the intestinal epithelium. Its ligands include bacterial heat-stable enterotoxins responsible for traveler's diarrhea, the endogenous peptide hormones uroguanylin and guanylin, and the synthetic agents,...

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Detalles Bibliográficos
Autores principales: Rappaport, Jeffrey A., Waldman, Scott A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6091576/
https://www.ncbi.nlm.nih.gov/pubmed/30131940
http://dx.doi.org/10.3389/fonc.2018.00299

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6091576/
https://www.ncbi.nlm.nih.gov/pubmed/30131940
http://dx.doi.org/10.3389/fonc.2018.00299

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