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Mitoregulin: A lncRNA-Encoded Microprotein that Supports Mitochondrial Supercomplexes and Respiratory Efficiency

Mitochondria are composed of many small proteins that control protein synthesis, complex assembly, metabolism, and ion and reactive oxygen species (ROS) handling. We show that a skeletal muscle- and heart-enriched long non-coding RNA, LINC00116, encodes a highly conserved 56-amino-acid microprotein...

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Detalles Bibliográficos
Autores principales: Stein, Colleen S., Jadiya, Pooja, Zhang, Xiaoming, McLendon, Jared M., Abouassaly, Gabrielle M., Witmer, Nathan H., Anderson, Ethan J., Elrod, John W., Boudreau, Ryan L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6091870/
https://www.ncbi.nlm.nih.gov/pubmed/29949756
http://dx.doi.org/10.1016/j.celrep.2018.06.002