Mathematical modeling of disease dynamics in SDHB- and SDHD-related paraganglioma: Further step in understanding hereditary tumor differences and future therapeutic strategies

Succinate dehydrogenase subunit B and D (SDHB and SDHD) mutations represent the most frequent cause of hereditary pheochromocytoma and paraganglioma (PPGL). Although truncation of the succinate dehydrogenase complex is thought to be the disease causing mechanism in both disorders, SDHB and SDHD pati...

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Detalles Bibliográficos
Autores principales: Barbolosi, Dominique, Crona, Joakim, Serre, Raphaël, Pacak, Karel, Taieb, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6091916/
https://www.ncbi.nlm.nih.gov/pubmed/30106970
http://dx.doi.org/10.1371/journal.pone.0201303

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6091916/
https://www.ncbi.nlm.nih.gov/pubmed/30106970
http://dx.doi.org/10.1371/journal.pone.0201303

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