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Mathematical modeling of disease dynamics in SDHB- and SDHD-related paraganglioma: Further step in understanding hereditary tumor differences and future therapeutic strategies
Succinate dehydrogenase subunit B and D (SDHB and SDHD) mutations represent the most frequent cause of hereditary pheochromocytoma and paraganglioma (PPGL). Although truncation of the succinate dehydrogenase complex is thought to be the disease causing mechanism in both disorders, SDHB and SDHD pati...
Autores principales: | Barbolosi, Dominique, Crona, Joakim, Serre, Raphaël, Pacak, Karel, Taieb, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6091916/ https://www.ncbi.nlm.nih.gov/pubmed/30106970 http://dx.doi.org/10.1371/journal.pone.0201303 |
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