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The Sec1/Munc18 (SM) protein Vps45 is involved in iron uptake, mitochondrial function and virulence in the pathogenic fungus Cryptococcus neoformans

The battle for iron between invading microorganisms and mammalian hosts is a pivotal determinant of the outcome of infection. The pathogenic fungus, Cryptococcus neoformans, employs multiple mechanisms to compete for iron during cryptococcosis, a disease primarily of immunocompromised hosts. In this...

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Detalles Bibliográficos
Autores principales: Caza, Mélissa, Hu, Guanggan, Nielson, Erik David, Cho, Minsu, Jung, Won Hee, Kronstad, James W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6091972/
https://www.ncbi.nlm.nih.gov/pubmed/30071112
http://dx.doi.org/10.1371/journal.ppat.1007220