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Tbx20 Is Required in Mid-Gestation Cardiomyocytes and Plays a Central Role in Atrial Development
RATIONALE: Mutations in the transcription factor TBX20 (T-box 20) are associated with congenital heart disease. Germline ablation of Tbx20 results in abnormal heart development and embryonic lethality by embryonic day 9.5. Because Tbx20 is expressed in multiple cell lineages required for myocardial...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092109/ https://www.ncbi.nlm.nih.gov/pubmed/29903739 http://dx.doi.org/10.1161/CIRCRESAHA.118.311339 |