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Tbx20 Is Required in Mid-Gestation Cardiomyocytes and Plays a Central Role in Atrial Development

RATIONALE: Mutations in the transcription factor TBX20 (T-box 20) are associated with congenital heart disease. Germline ablation of Tbx20 results in abnormal heart development and embryonic lethality by embryonic day 9.5. Because Tbx20 is expressed in multiple cell lineages required for myocardial...

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Detalles Bibliográficos
Autores principales: Boogerd, Cornelis J., Zhu, Xiaoming, Aneas, Ivy, Sakabe, Noboru, Zhang, Lunfeng, Sobreira, Debora R., Montefiori, Lindsey, Bogomolovas, Julius, Joslin, Amelia C., Zhou, Bin, Chen, Ju, Nobrega, Marcelo A., Evans, Sylvia M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092109/
https://www.ncbi.nlm.nih.gov/pubmed/29903739
http://dx.doi.org/10.1161/CIRCRESAHA.118.311339