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Efficient support of virus-like particle assembly by the HIV-1 packaging signal

The principal structural component of a retrovirus particle is the Gag protein. Retroviral genomic RNAs contain a ‘packaging signal’ (‘Ψ') and are packaged in virus particles with very high selectivity. However, if no genomic RNA is present, Gag assembles into particles containing cellular mRNA...

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Detalles Bibliográficos
Autores principales: Comas-Garcia, Mauricio, Kroupa, Tomas, Datta, Siddhartha AK, Harvin, Demetria P, Hu, Wei-Shau, Rein, Alan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092119/
https://www.ncbi.nlm.nih.gov/pubmed/30070634
http://dx.doi.org/10.7554/eLife.38438