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Efficient support of virus-like particle assembly by the HIV-1 packaging signal
The principal structural component of a retrovirus particle is the Gag protein. Retroviral genomic RNAs contain a ‘packaging signal’ (‘Ψ') and are packaged in virus particles with very high selectivity. However, if no genomic RNA is present, Gag assembles into particles containing cellular mRNA...
Autores principales: | Comas-Garcia, Mauricio, Kroupa, Tomas, Datta, Siddhartha AK, Harvin, Demetria P, Hu, Wei-Shau, Rein, Alan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092119/ https://www.ncbi.nlm.nih.gov/pubmed/30070634 http://dx.doi.org/10.7554/eLife.38438 |
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