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Controlling load-dependent kinetics of β-cardiac myosin at the single molecule level
Concepts in molecular tension sensing in biology are growing and have their origins in studies of muscle contraction. In the heart muscle, a key parameter of contractility is the detachment rate from actin of myosin, which determines the time that myosin is bound to actin in a force-producing state...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092189/ https://www.ncbi.nlm.nih.gov/pubmed/29867217 http://dx.doi.org/10.1038/s41594-018-0069-x |