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Controlling load-dependent kinetics of β-cardiac myosin at the single molecule level

Concepts in molecular tension sensing in biology are growing and have their origins in studies of muscle contraction. In the heart muscle, a key parameter of contractility is the detachment rate from actin of myosin, which determines the time that myosin is bound to actin in a force-producing state...

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Detalles Bibliográficos
Autores principales: Liu, Chao, Kawana, Masataka, Song, Dan, Ruppel, Kathleen M., Spudich, James A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092189/
https://www.ncbi.nlm.nih.gov/pubmed/29867217
http://dx.doi.org/10.1038/s41594-018-0069-x