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Analysis of the genomic landscape of multiple myeloma highlights novel prognostic markers and disease subgroups

In multiple myeloma, next-generation sequencing (NGS) has expanded our knowledge of genomic lesions, and highlighted a dynamic and heterogeneous composition of the tumor. Here we used NGS to characterize the genomic landscape of 418 multiple myeloma cases at diagnosis and correlate this with prognos...

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Detalles Bibliográficos
Autores principales: Bolli, Niccolo, Biancon, Giulia, Moarii, Matahi, Gimondi, Silvia, Li, Yilong, de Philippis, Chiara, Maura, Francesco, Sathiaseelan, Vijitha, Tai, Yu-Tzu, Mudie, Laura, O’Meara, Sarah, Raine, Keiran, Teague, Jon W., Butler, Adam P., Carniti, Cristiana, Gerstung, Moritz, Bagratuni, Tina, Kastritis, Efstathios, Dimopoulos, Meletios, Corradini, Paolo, Anderson, Kenneth C., Moreau, Philippe, Minvielle, Stephane, Campbell, Peter J., Papaemmanuil, Elli, Avet-Loiseau, Herve, Munshi, Nikhil C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092251/
https://www.ncbi.nlm.nih.gov/pubmed/29789651
http://dx.doi.org/10.1038/s41375-018-0037-9