Proximal Cysteines that Enhance Lysine N-Acetylation of Cytosolic Proteins in Mice Are Less Conserved in Longer-Living Species

Acetyl-coenzyme A (CoA) is an abundant metabolite that can also alter protein function through non-enzymatic N-acetylation of protein lysines. This N-acetylation is greatly enhanced in vitro if an adjacent cysteine undergoes initial S-acetylation, as this can lead to S→N transfer of the acetyl moiet...

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Detalles Bibliográficos
Autores principales: James, Andrew M., Smith, Anthony C., Smith, Cassandra L., Robinson, Alan J., Murphy, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092265/
https://www.ncbi.nlm.nih.gov/pubmed/30089256
http://dx.doi.org/10.1016/j.celrep.2018.07.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092265/
https://www.ncbi.nlm.nih.gov/pubmed/30089256
http://dx.doi.org/10.1016/j.celrep.2018.07.007

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