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Neuronal Mitochondrial Dysfunction Activates the Integrated Stress Response to Induce Fibroblast Growth Factor 21

Stress adaptation is essential for neuronal health. While the fundamental role of mitochondria in neuronal development has been demonstrated, it is still not clear how adult neurons respond to alterations in mitochondrial function and how neurons sense, signal, and respond to dysfunction of mitochon...

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Detalles Bibliográficos
Autores principales: Restelli, Lisa Michelle, Oettinghaus, Björn, Halliday, Mark, Agca, Cavit, Licci, Maria, Sironi, Lara, Savoia, Claudia, Hench, Jürgen, Tolnay, Markus, Neutzner, Albert, Schmidt, Alexander, Eckert, Anne, Mallucci, Giovanna, Scorrano, Luca, Frank, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092266/
https://www.ncbi.nlm.nih.gov/pubmed/30089252
http://dx.doi.org/10.1016/j.celrep.2018.07.023