Use of Precision-Cut Lung Slices as an Ex Vivo Tool for Evaluating Viruses and Viral Vectors for Gene and Oncolytic Therapy

Organotypic slice cultures recapitulate many features of an intact organ, including cellular architecture, microenvironment, and polarity, making them an ideal tool for the ex vivo study of viruses and viral vectors. Here, we describe a procedure for generating precision-cut ovine and murine tissue...

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Detalles Bibliográficos
Autores principales: Rosales Gerpe, María C., van Vloten, Jacob P., Santry, Lisa A., de Jong, Jondavid, Mould, Robert C., Pelin, Adrian, Bell, John C., Bridle, Byram W., Wootton, Sarah K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092314/
https://www.ncbi.nlm.nih.gov/pubmed/30112421
http://dx.doi.org/10.1016/j.omtm.2018.07.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092314/
https://www.ncbi.nlm.nih.gov/pubmed/30112421
http://dx.doi.org/10.1016/j.omtm.2018.07.010

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