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Keap1–MCM3 interaction is a potential coordinator of molecular machineries of antioxidant response and genomic DNA replication in metazoa

Coordination of DNA replication and cellular redox homeostasis mechanisms is essential for the sustained genome stability due to the sensitivity of replicating DNA to oxidation. However, substantial gaps remain in our knowledge of underlying molecular pathways. In this study, we characterise the int...

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Detalles Bibliográficos
Autores principales: Tamberg, Nele, Tahk, Siret, Koit, Sandra, Kristjuhan, Kersti, Kasvandik, Sergo, Kristjuhan, Arnold, Ilves, Ivar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092318/
https://www.ncbi.nlm.nih.gov/pubmed/30108253
http://dx.doi.org/10.1038/s41598-018-30562-y