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Isoform-Specific Compensation of Cyclooxygenase (Ptgs) Genes during Implantation and Late-Stage Pregnancy

The participation of cyclooxygenase (COX) in embryo implantation and parturition has been studied extensively. However, the distinct role of the two COX isoforms in these processes still remains unclear. Using three characterized mouse lines where the Ptgs1 and Ptgs2 genes substitute for one another...

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Detalles Bibliográficos
Autores principales: Li, Xinzhi, Ballantyne, Laurel L., Crawford, Mackenzie C., FitzGerald, Garret A., Funk, Colin D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092371/
https://www.ncbi.nlm.nih.gov/pubmed/30108257
http://dx.doi.org/10.1038/s41598-018-30636-x