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Integrative metagenomic and biochemical studies on rifamycin ADP-ribosyltransferases discovered in the sediment microbiome

Antibiotic resistance is a serious and growing threat to human health. The environmental microbiome is a rich reservoir of resistomes, offering opportunities to discover new antibiotic resistance genes. Here we demonstrate an integrative approach of utilizing gene sequence and protein structural inf...

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Detalles Bibliográficos
Autores principales: Shin, Jae Hong, Eom, Hyunuk, Song, Woon Ju, Rho, Mina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092378/
https://www.ncbi.nlm.nih.gov/pubmed/30108275
http://dx.doi.org/10.1038/s41598-018-30547-x