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Integrative metagenomic and biochemical studies on rifamycin ADP-ribosyltransferases discovered in the sediment microbiome
Antibiotic resistance is a serious and growing threat to human health. The environmental microbiome is a rich reservoir of resistomes, offering opportunities to discover new antibiotic resistance genes. Here we demonstrate an integrative approach of utilizing gene sequence and protein structural inf...
Autores principales: | Shin, Jae Hong, Eom, Hyunuk, Song, Woon Ju, Rho, Mina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092378/ https://www.ncbi.nlm.nih.gov/pubmed/30108275 http://dx.doi.org/10.1038/s41598-018-30547-x |
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