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A Mixture of Atropisomers Enhances Neutral Lipid Degradation in Mammalian Cells with Autophagy Induction

Atropisomers with a biaryl dihydronaphthopyranone structure, dinapinones A1 (DPA1) (M position) and A2 (DPA2) (P position), were isolated from the fungus culture broth of Talaromyces pinophilus FKI-3864 as inhibitors of [(14)C]neutral lipid ([(14)C]triacylglycerol (TG) and [(14)C]cholesteryl ester (...

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Detalles Bibliográficos
Autores principales: Kobayashi, Keisuke, Ohte, Satoshi, Ohshiro, Taichi, Ugaki, Narihiro, Tomoda, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092391/
https://www.ncbi.nlm.nih.gov/pubmed/30108268
http://dx.doi.org/10.1038/s41598-018-30679-0