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Dual action of the Gα(q)-PLCβ-PI(4,5)P(2) pathway on TRPC1/4 and TRPC1/5 heterotetramers

The transient receptor potential canonical (TRPC) 1 channel is widely distributed in mammalian cells and is involved in many physiological processes. TRPC1 is primarily considered a regulatory subunit that forms heterotetrameric channels with either TRPC4 or TRPC5 subunits. Here, we suggest that the...

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Detalles Bibliográficos
Autores principales: Myeong, Jongyun, Ko, Juyeon, Kwak, Misun, Kim, Jinsung, Woo, Joohan, Ha, Kotdaji, Hong, Chansik, Yang, Dongki, Kim, Hyun Jin, Jeon, Ju-Hong, So, Insuk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092394/
https://www.ncbi.nlm.nih.gov/pubmed/30108272
http://dx.doi.org/10.1038/s41598-018-30625-0