Targeting proinflammatory cytokines ameliorates calcifying phenotype conversion of vascular progenitors under uremic conditions in vitro

Severe vascular calcification develops almost invariably in chronic kidney patients posing a substantial risk to quality of life and survival. This unmet medical need demands identification of novel therapeutic modalities. We aimed to pinpoint components of the uremic microenvironment triggering dif...

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Detalles Bibliográficos
Autores principales: Hegner, Björn, Schaub, Theres, Janke, Daniel, Zickler, Daniel, Lange, Claudia, Girndt, Matthias, Jankowski, Joachim, Schindler, Ralf, Dragun, Duska
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092400/
https://www.ncbi.nlm.nih.gov/pubmed/30108259
http://dx.doi.org/10.1038/s41598-018-30626-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092400/
https://www.ncbi.nlm.nih.gov/pubmed/30108259
http://dx.doi.org/10.1038/s41598-018-30626-z

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